The study was focused on the evaluation of phytochemicals and hypnotic potential of ethanolic extract of Saccharum Bengalense. Tripidium bengalense, often known as munj grass and found in arid areas and along riverbanks, is synonymized as Saccharum benghalense. The shrub Saccharum bengalense was procured from the Unnao area of India. A botanist recognized and verified these; they were then cleaned to remove dust and dried at room temperature. The dried plant was ground into first coarse and then fine powders. After weighing, the powder was steeped in 95% ethanol for fifteen days, stirring gradually during that time. The preliminary phytochemical screening was performed for the herbal extract. Albino rats weighing 130–150g was provided by the animal house, Institute of Pharmaceutical Sciences and Research, Unnao. They were housed in environment, with a 12-hour light/dark cycle and at room temp. (25°C). The rats were kept in 4 groups; n=6 & dosed for 21 days i.e., group 1: treated with normal saline, group 2: treated with Diazepam (4mg/kg) orally, group 3: treated with ethanolic extracts of Saccharum bengalense (EESB) (200mg/kg) orally and group 4: treated with ethanolic extracts of Saccharum bengalense (EESB) (400mg/kg) orally. Evaluation parameters i.e., thiopental sod. induced sleeping time, motor co-ordination test, light-dark arena model and locomotion activity were performed. In results, the percentage yield of Saccharum bengalense extract was found to be 63.12%. At 200mg/kg and 400mg/kg, the ethanolic extract of Saccharum bengalense exhibited a dose-dependent increase in activity, scoring 131±0.29** and 102±0.32**, respectively. It concludes that Saccharum bengalense ethanolic extract effectively reduces insomnia symptoms and enhances mental well-being during sleep induction. It suggests the separation of the major active ingredients in Saccharum bengalense that are involved in activity, followed by their conversion into a dosage form that facilitates absorption.
